To condition the system to an initial state, use a time-dependent outgassing that desorbs some particles in the beginning, optionally with a “valve” facet that has time-dependent opacity to contain particles to the desired volume.
As vacuum systems are linear, with one scaling step you can find the exact outgassing value that achieves the required target pressure.
Use the Pressure evilution plotter to monitor the pressure buildup in the initially pressurized volume, and open the valve when the pressure has stabilized.
You would need to create/use a facet that will serve as gas source -> for its outgassing value, give a parameter name, for example "outgassing1".
You will also need to delimit the initial volume by a valve facet (so the initially injected gas won't escape to other parts of the system) -> let its opacity value be time-dependent as well, let's say "valve1"
Now you have to control these two facets in the parameter editor (Time / Edit Parameters):
Let Outgassing1 be a parameter of pulse desorption. For example, at moment 0, let its value be 1, and at moment 1E-7 s, let its value be 0. That way all molecules will be inserted at the very beginning.
Depending on the size and gas type of your system, the initial volume will need some time to reach equilibrium. Until that happens, keep the valve closed. Therefore the parameter "valve1" would be defined as 1 (total opacity) at moment t (if t is the time when equilibrium is reached), and 0 (full transparency) shortly after. If, for example, the valve opening moment is 1s, then the parameter would look like this: 1s -> value 1, 1.0001s -> value 0